| abstract |
A new method for the inhibition of human sweating and body malodour is described. An agent capable of blocking calcium channels in the secretory coil cells of human sweat glands is topically applied; on reaching the secretory coil cells, the action of this agent results in reduced sweat production. Preferred agents are natural plant extracts. The transport of the agent to the secretory coil is preferably enhanced in some way, for example by iontophoresis or the use of a skin penetration enhancer. Antiperspirant products comprising a calcium channel blocking agent and a pore-blocking antiperspirant active are also claimed. |