abstract |
Microarrays are prepared by using a separate fiber for each compound being used in the microarray. The fibers are bundled and sectioned to form a thin microarray that may be glued to a backing. The present invention also discloses uses and methods for manufacture of microarrays constructed in part by sectioning bundles of tubules or rods containing matrix immobilized bioreactive molecules to produce large numbers of sample chips. The chips so produced are processed by deposition to microarrays. The deposited chips can than be manipulated to partition the immobilizing matrix away from the bioreactive molecules contained in the matrix and to place said partitioned molecules onto various surfaces for subsequent analysis, to include binding assays, hybridization reactions, diagnostic methods and a variety of cell interaction-determining methodologies. |