| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f4dfbf7e928b2477534a09534993e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dd0759950a6de264b065af44e0f1840
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_541baa04b328f148775bd9f5cc81ab16 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-868 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 |
| filingDate |
2002-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0794c87191a6063f6ccfbea486cf83ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_258f8fd993caea6fcee3222af19691cd |
| publicationDate |
2002-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02102852-A2 |
| titleOfInvention |
Modified cd8 molecule, nucleic acid encoding said molecule, and their therapeut ic use |
| abstract |
The present invention provides modified CD8 molecules whose binding to MHC is enhanced compared to wild type CD8, wherein Ser53 of at least one CD8α chain thereof is mutated to another amino acid. It also provides nucleic acids encoding such molecules, and to the use of such molecules and nucleic acids in immunosuppressive therapy, in particular as inhibitors of cytotoxic T cell responses. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022112752-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9169493-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004083244-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004083244-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8871515-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9719107-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006012416-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006520604-A |
| priorityDate |
2001-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |