http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02102842-A8
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c95780a4f543b131f4f1bdf6a028b89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcf180a46b7fb0fd489508e4e2447e61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50856616518d21e3a7d9339aa7eb5a96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eb13333226b5aa8bf383b159c00bb62 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate | 2002-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0fad3d15f32983aa74f89cc856e6dc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acc13c75354ba96cf5a8564879e34c39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a91bb60de307c6b878de5e5472b0435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed935fb577eba0c3e5dd03b3f07cceeb |
publicationDate | 2004-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-02102842-A8 |
titleOfInvention | Immunogenic helicobacter surface proteins and their use |
abstract | An isolated or recombinant immunogenic Helicobacter species surface protein selected from the group consisting of immunogenic H. pullorum, H. bilis and H. hepaticus surface proteins, and obtainable by cultivating the respective Helicobacter sp. bacteria in vitro, isolating the cultivated bacteria, releasing surface proteins by extraction with acid glycine or water, removing the bacteria, and subjecting the obtained protein mixture to separation by a two dimensional immunoblot gel-electrophoresis (2-DE) and identifying specific immunogenic proteins from each Helicobacter species after cross-absorption by two dimensional 2- DE immunoblotting, followed by isolation of the immunoblotting, followed by isolation of the immunogenic protein and optionally sequencing of the protein followed by recombinant production of the protein, is described. Further, the use of surface proteins or mixture thereof as diagnostic antigens in immunodiagnostic tests, two methods of in vitro diagnosing liver, pancreas and bile tract diseases/ syndromes, including inflammatory bowel disease (IBD), caused by Helicobacter species or related species, and an antibody raised against a disclosed surface protein, are described. |
priorityDate | 2001-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.