http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02102765-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_948e319e91997d33dd6c0c20ec8f7efa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec5b8c0fc1f827c1360a8f5ea5652225 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
| filingDate | 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb7976b127db9c39bd427eab010ddd6b |
| publicationDate | 2003-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02102765-A3 |
| titleOfInvention | Protected tyrosine derivatives, method for the production thereof and use of the same for producing o-(2-[18f]-fluoroethyl)-l-tyrosine |
| abstract | The compound O-(2-[18F]fluoroethyl)-L-tyrosine has proven to be particularly suitable for positron emission tomography and has already been tested in clinical practice. Until now, the compound has been produced according to a relatively laborious method (Wester H.J. et al.; J. Nucl. Med. 1999; 40: 205-212). The invention relates to L-tyrosine derivatives of formula (1), wherein R1 represents a suitable protective group for the carboxy group, R2 represents a suitable protective group for the amino group, and R3 represents a suitable leaving group. R1 represents a methylthiomethyl group, a tetrahydrofuranyl group, a diphenylmethyl group, a para-methoxybenzyl group, a piperonyl group or a tert-butyl group, R2 represents an alkyl group or an arylalkyl group, and R3 represents a p-tosyloxy, methanesulfonyloxy, trifluoromethanesulfonyloxy or bromine. The invention also relates to a method for producing O-(2-[18F]-fluoroethyl)-L-tyrosine from the parent compounds of formula (1) and to a method for producing said parent compounds. |
| priorityDate | 2001-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.