| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10e4b1416c6e66e0ade5429212414964
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9dfb453aadc17efcb1825087af69f778
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e10b67dbbcb424328ed8fbfe68019b44 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate |
2002-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b52fd5ef35e194ac89d4a8b95e9b32d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67806eb58c32dcc7fad0ff9d79dccb8e |
| publicationDate |
2003-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02100829-A3 |
| titleOfInvention |
Process for the preparation of paroxetine substantially free of alkoxy impurities |
| abstract |
The present invention is directed to methods for preparing intermediates useful in the synthesis of paroxetine wherein the intermediates are substantially free of alkoxy impurities as well as to methods for preparing paroxetine and pharmaceutically acceptable salts thereof substantially free of alkoxy impurities. The alkoxy impurity is reacted with an ether cleaving agent to generate to corresponding phenol, which is separated, yielding the desired product substantially free of alkoxy impurities. Paroxetine intermediates such as PMA, paroxetine, and pharmaceutically acceptable salts thereof substantially free of alkoxy impurities also form part of the present invention. |
| priorityDate |
2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |