http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02099136-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b21f650fc35b3e1947103e89adb06f3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e31eb520f2df25fb665c7bc6e9aa774 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16222 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-05 |
| filingDate | 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d1111dca527509e90715e03a53e253b |
| publicationDate | 2002-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02099136-A1 |
| titleOfInvention | Methods and compositions fir identifying episomal dna virus infection treatment |
| abstract | Compounds useful in the treatment of infection by an episomal DNA virus are identified by a method involving the steps of (1) providing a culture of mammalian or avian cells containing multiple copies of a recombinant viral extrachromosomal episome having an episomal maintenance element, the episomes being associated with a detectable label; (2) contacting the culture with a test molecule that inhibits the interaction between the episomal maintenance element on the episomes and at least one enzyme selected from a family of enzymes consisting of the poly-ADP ribose polymerase family, the poly-ADP glycosylase family, the telomerase family, the myb DNA binding family that interferes with telomeres, and the telomere repeat binding protein family; and (3) detecting the elimination of the episomes from the cells by detecting the presence of the detectable label in the medium of the culture. These compositions are useful in pharmaceutical compositions for treating an infection by an episomal DNA virus and in diagnostic kits. |
| priorityDate | 2001-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.