abstract |
The present invention relates to a new method for measuring apolipoprotein CIII ('apo CIII') in apo B and non apo B containing lipoparticles. This invention also relates to synthetic apo CIII products, corresponding antibodies, kits comprising the same, and their use to detect, quantify and/or monitor apo CIII levels in a sample, as well as to quantify and/or monitor atherogenic lipoparticle levels in a sample. The above compounds and kits can also be used to modulate apo CIII levels or activity in vitro or in vivo, and to regulate lipid metabolism in a subject. |