abstract |
A novel glucose derivative inducing apoptosis. The glucose derivative is represented by the following general formula (I) wherein X, Y and Z are the same or different and each is hydrogen, halogenoalkyl, hydroxy, or alkoxy, provided that not all of X, Y and Z are hydrogen; R1, R2, and R3 are the same or different and each is hydrogen or acyl (COR4), provided that not all of R1, R2, and R3 are hydrogen; and R4 is an (un)saturated, linear or branched, C3-25 hydrocarbon group. The glucose derivative selectively induces apoptosis in unnecessary or pathogenic cells. It is hence useful as a medicine for the treatment and/or prevention of diseases attributable to the cells. |