Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a103cb9bdf23437a9fa50ca11a529b27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85df5643a83498ce5fc1ed1cbac2cfc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1d8cea88f2f13897e460a36ab3ca0b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c46a41399d2b7b55df9f15770398c31a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2002-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a763950f659c1ac298466a788a5b2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f573f03badfcbdb63bbe726bcb6ceb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9b369be42acbc8ed90d27b032502d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6364e8918406f11f5c7d30bd6171028f |
publicationDate |
2002-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-02095008-A2 |
titleOfInvention |
Methods of modulating surfactant phospholipid production |
abstract |
The present invention provides methods for modulating surfactant production using SREBP/ADD-1 polypeptides, and agonists or antagonists that are capable of modulating SREBP/ADD-1 activity. More particularly, the present invention encompasses the use of SREBP/ADD-1 polypeptides or agonist or antagonist polypeptides for the treatment of a disease or clinical condition where surfactant production is relevant to the causation or treatment of the disease or clinical condition, such as lung diseases, including adult/infant respiratory distress syndrome, acute lung injury, chronic obstructive pulmonary disease (emphysema and chronic bronchitis), asthma, alveolar proteinosis and related pulmonary conditions. The present invention also encompasses pharmaceutical compositions containing the SREBP/ADD-1 polypeptides or agonist or antagonist polypeptides and the use of such pharmaceutical compositions for the treatment of the above-mentioned diseases or clinical conditions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017191165-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10655111-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109415748-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4893893-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006082916-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434474-B2 |
priorityDate |
2001-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |