http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02090519-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2002-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eba8e93b510c2ef6a636ceefebfe8961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9803883c5c6d7c090678489dfef30499 |
| publicationDate | 2002-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02090519-A2 |
| titleOfInvention | Mutant p21?cip1/waf1¿ and cell growth control |
| abstract | Disclosed are methods and compositions regarding separate mutant forms of p21?Cip/WAF1¿ that are associated with control of cell growth. Substitution of Thr145 with another amino acid, such as Ala, results in failure to be phosphorylate at that site and leads to retention of the polypeptide in the nucleus, resulting in preferentially suppressing growth of transformed cells. Alternatively, substitution of Thr145 with another amino acid, such as Asp, results in cytoplasmic translocation of the polypeptide and results in enhancing cellular survival. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005040207-A1 |
| priorityDate | 2001-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1830.