| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4748ede28f585244804d0cf8dbb94669
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5012d58bb33dc9709ccad873df226cd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91eb4d0b351e58fc9f7ffce4554acd01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8878ea9f6d45fe5bbb281854395916df |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate |
2002-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91bbd73b44c3fa1f170855a566054412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61da907d53b3153316b876147a0ebfb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_507036ce2523ca6a991f7bbad347326e |
| publicationDate |
2002-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02089855-A1 |
| titleOfInvention |
Peroral transduction of hepatocytes in the treatment of disease |
| abstract |
There is disclosed a method of expressing a therapeutically effective amount of a biologically active protein or peptide in a hepatocyte comprising oral administration of a vector, or of a therapeutic agent comprising the vector, wherein the vector comprises a nucleotide sequence encoding the protein or peptide operably linked to a regulatory sequence capable of driving expression of the nucleotide sequence in the hepatocyte, and wherein the hepatocyte harbouring the vector secretes the expressed protein or peptide into the systemic circulation locally. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012047091-A1 |
| priorityDate |
2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |