| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d0446a5bd77c7da68216fc2e3f05d48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36e3eb09c3eec0f9f3e884998b70dc00 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16643
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245 |
| filingDate |
2002-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8e389a68df9f79f795cfac1687a15eb |
| publicationDate |
2002-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02087625-A1 |
| titleOfInvention |
Composite oncolytic herpes virus vectors |
| abstract |
A highly efficient and safe HSV derived composite oncolytic vector is provided for the treatment of solid tumors in an individual. The vector comprises two main components being a defective viral genome with multiple reiterations of amplicon type repeat units each carrying inducible toxic genes with cell destructive capabilities and, as a second component, an HSV mutant helper virus which is incapable of replication in non-dividing cells. The vector may be used for the treatment of various kinds of solid tumors including brain malignancies as well as lung, pancreatic, kidney, colon, stomach and other types of cancers. The provided vector is also suitable for administration to an individual in combination with an additional treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8092791-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119118-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7361354-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020109389-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7485292-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8722036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004064765-A3 |
| priorityDate |
2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |