| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a3f5a0bf829b1fa4b8a24f9d9125f7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61b5d89f31cd2e34e42e680280852358
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2d084871cdf3dd9000e910128b1d27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8be8e05b49c4667721b5fc6f9792041e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-445 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate |
2002-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d18fe675752adf01a466bce50af4a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cc4cbe5a1730f9f06098183d4c79090
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a72bbdc0b569f96145122e533f489f6 |
| publicationDate |
2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02085947-A1 |
| titleOfInvention |
Soluble protein from malaria parasite |
| abstract |
The present invention relates to a method of producing soluble antigenic proteins from a malaria parasite and recovery under non-denaturing conditions, as well as to the production of malaria vaccines thereby. Accordingly, the present invention provides a process of obtaining a non-glycosylated a malaria parasite merozoite surface protein 1 19 kDa C-terminal polypeptide (MSP-119) expressed in soluble form in a prokaryotic host cell without the provision of a fusion partner to assist folding of said MSP-119, said process comprising recovering said MSP-l polypeptide from said cell under non-reducing conditions. It also provides polypeptides produced by such processes and pharmaceutical compositions, especially vaccine compositions, comprising them. |
| priorityDate |
2001-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |