http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02085856-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_686552805c862e86742c207a619ebde9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29f910735b06460b1c25ceca2dab478b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13ce4154585466663955521902b67676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b7e69ff97642b30acf1a2fdba65bdc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2002-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1555ea66624c496bd937fbd59da81a26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a9ec03db2b14535656b35aa83a6a8a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7186791e947499fe906242b50ac582d5 |
| publicationDate | 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02085856-A1 |
| titleOfInvention | Synthesis and methods of use of tetrahydroindolone analogues and derivatives |
| abstract | A tetrahydroindolone derivative or analogue comprises a 9-atom bicyclic moiety, moiety A, linked through a linker L to a moiety B, where B is a carboxylic acid, a carboxylic acid ester, or a moiety of the structure N(Y1)-D, where Y1 can be one of a variety of substituents, including hydrogen or alkyl, and D is a moiety that enhances the pharmacological effects, promotes absorption or blood-brain barrier penetration of the derivative or analogue. The moiety A has a six-membered ring fused to a five-membered ring. The moiety A can be have one, two, or three nitrogen atoms in the five membered ring. The moiety A can be a tetrahydroindolone moiety. The moiety B can be one of a variety of moieties, including moieties having nootropic activity or other biological or physiological activity. In general, a bifunctional conjugate according to the present invention has the schematic structure (1) where A is a 9-atomic bicycle moiety in which the five-membered ring has 1 to 3 nitrogen atoms, the bicyclic moiety having the structure (2). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091447-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007101156-A1 |
| priorityDate | 2001-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.