http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0208280-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7ff1190e0c5e12e95f0243e5850e0e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2c2459d9831616925869af1a2de323e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16b4b925c174c5f4ad9246020e8b1e11 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70557 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate | 2001-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f718dba6dbf15308de5893bd09d6eb66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b77adcaee52cb8d3b3bf8a71a0a2777a |
| publicationDate | 2002-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0208280-A2 |
| titleOfInvention | SCREENING METHODS BASED ON SUPERACTIVATED αVβ3 INTEGRIN |
| abstract | The present invention is directed to a method of identifying an inhibitor or enhancer of αvβ3 activity by contacting superactivated αvβ3 integrin with one or more molecules; and assaying an αvβ3 integrin activity, where reduced αvβ3 identifies an inhibitor of αvβ3 activity and where enhanced αvβ3 activity identifies an enhancer of αvβ3 activity. In a preferred embodiment, a cell, such as a MCF-7 breast carcinoma cell, is transfected with a nucleic acid molecule encoding a superactivated β3 variant, which can have, for example, substantially the amino acid sequence of SEQ ID NO: 6 shown in Figure 3. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115433261-A |
| priorityDate | 2000-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 380.