| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59521475287528d32c66fee9397cd1e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70ceca22c7895dab6d47243d0d2cfe22 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c328007aa5d75d128813e01694e285 |
| publicationDate |
2002-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02081688-A1 |
| titleOfInvention |
Dna molecules encoding igb3 synthase, and uses thereof for the disruption of glycosyltransferase genes in xenotransplantation tissues and organs |
| abstract |
Nucleic acid molecules encoding iGb3 synthase are disclosed, as well as fragments and mutants thereof. IGb3 synthase is, in part, responsible for the production of a Gal?a(1,3)Gal epitope in xenograft cells, tissues and organs which in humans provokes hyperacute rejection (HAR). The nucleic acid molecules of the invention may be used to generate animals in which the iGb3 synthase gene is disrupted. The cells, tissues and organs harvested from such animals are therefore useful in xenotransplantation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7547816-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101843427-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101931617-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1465481-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1465481-A4 |
| priorityDate |
2001-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |