http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02080898-A3

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filingDate 2002-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70b43db6fbc433708ee79628fdb5a085
publicationDate 2003-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-02080898-A3
titleOfInvention Methods for treating hyperactive gastric motility
abstract This invention provides methods and pharmaceutical compositions for treating, inhibiting or preventing hyperactive gastric motility in a mammal utilizing agonists of KCNQ potassium channels, including KCNQ2, KCNQ3, KCNQ4 and KCNQ5 potassium channels, alone or in combination. The hyperactive gastric motility may be associated with maladies including, colitis, irritable bowel syndrome and Crohn's disease. Compounds useful in these methods include the 1,2,4-triamino-benzene derivatives described in U.S. Patent No. 5,384,330 (Dieter et al.) and the substituted 3-phenyl oxindole compounds described in U.S. Patent No. 5,565,483 (Hewawasam et al.). Among the preferred compounds of this invention is N-[2-amino-4-(4-fluorobenzylamino)-phenyl]carbamic acid ethyl ester, also referred to as retigabine.
priorityDate 2001-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 33.