| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b1f1d7442263497d426f2d24a644ddf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cc95d067372bee0ae936851e1015457
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4555f9a345961df791894695209d3273 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-643 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e881bf610c40982b4c9c7389e86d300c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d085a8f4b35e22d2b5efba6bf2e2611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10df2623422222f8a9aaea9c42b926b3 |
| publicationDate |
2002-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02077025-A1 |
| titleOfInvention |
Peptide analogues of myelin basic protein epitopes in the treatment of experimental autoimmune encephalomyelitis (eae) and multiple sclerosis (ms) |
| abstract |
This invention relates to novel linear and cyclic peptide analogues of Myelin Basic Protein epitopes (from guinea pig MBP72-85 and human MBP87-99) and their conjugates with mannan and/or KLH useful in the treatment of Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS). For the first time cyclic analogues of MBP epitopes have been synthesized and shown to prevent the development of EAE. There is gathering evidence that analogues of disease-associated epitopes can be conjugated to mannan and/or KLH and actively generate antigen specific regulatory CD4/CD8 T cells and Th1/Th2 cytokines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102393-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102393-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100791996-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2197898-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2197898-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2737906-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2009207345-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9517253-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009093143-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018127829-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9180174-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10472393-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009093143-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9546198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014200921-B2 |
| priorityDate |
2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |