| abstract |
This invention provides a polymer-based intracellular delivery system for protein phosphatases and other polypeptides. This delivery system can be used to deliver polypeptides for anti-tumor, anti-inflammatory, or immunosuppressive therapy, for treatment of genetic disorder or disease, and for therapy of any condition which requires intracellular delivery of polypeptides. Preferred embodiments according to the invention utilize acrylamide based polymers, most preferably copolymers comprising hydroxypropyl methacrylamide. |