Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41f8da5bacc9cf402087975b7a26f782 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43545 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2002-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35793481c55e947ee1bd96005d891053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a36dd073f7e26a9f246912a060162108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_032a1eaa851c49b9d8e16c5a694ab3c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05a25f28ff1b15fa0386ed59b79c052c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b8d64a21db36705b51c4b67aaa1563 |
publicationDate |
2002-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-02074923-A9 |
titleOfInvention |
Targets and screens for agents useful in controlling parasitic nematodes |
abstract |
The invention provides methods and reagents for identifying compounds that exhibit anti-nematode activity and compounds that potentiate the effects of other anti-nematode agents. The invention provides methods foridentifying modulators of nematode xenobiotic sensing nuclear receptors. The invention also provides methods for screening for anti-nematode compounds using sensitized nematode strains and further provides such sensitized strains. The invention further provides methods and screens for identifying new biological targets for anti-nematode compounds, e.g., for identifying nematode genes and proteins towards which anti-nematode compounds can be developed. The invention provides methods for controlling parasitic nematodes using compounds identified in the inventive screens. In addition, the invention provides sensitized nematode strains and methods for using such strains to enhance identification of compounds in the context of a wide variety of nematode model screening systems and strains. |
priorityDate |
2001-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |