| abstract |
In one aspect, the present invention provides methods for modulating neural activity in the retina of a mammalian eye, wherein the methods each comprise the step of irradiating the retina of a mammalian eye with light energy (14,16,18,22,26), wherein: (a) the retina comprises a photoactivatable precursor molecule comprising a neuroactive molecule linked to a photoabsorbent molecule; and (b) the light energy releases the neuroactive molecule from the photoabsorbent molecule, the released neuroactive molecule interacting with one or more retinal neurons thereby modulating neural activity in the retina. |