http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02072891-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7a5dc3c62f9b72c71a49dc4298838d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0ffc676c186d2b4dbc0cf08a14ff817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc3404b12045dfaf54945715874676c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259739d9733990a3c01ca3601a442e37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2002-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c7126e8dde0b0784781f57ab416d7df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6722adb8890cb8a8fad4bf1a23c14814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a4ea345b28eaf0a788cb3df892085e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3f095ca5fffd1e22f16cfa01652276a |
| publicationDate | 2002-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02072891-A1 |
| titleOfInvention | Fluorescence assay for dna modifying enzymes |
| abstract | A method of assaying compounds for their ability to effect enzymes including enhancing or inhibiting the effect of those enzymes on double stranded DNA sequences is disclosed. The method comprises providing a modified nucleotide sequence comprised of a base analogue which analogue is characterized by increased fluorescence when moved out of its normal helical position, the sequence having a complimentary sequence hybridized thereto to provide a double stranded sequence. The modified sequence containing the base analogue is brought into contact with the enzyme which enzyme is characterized by effecting the 3-dimensional position of the analogue within the sequence. The enzyme is brought into contact with the sequences in the presence of a compound being assayed. By knowing the amount of increased fluorescence the enzyme would normally have on the sequence is possible to determine the inhibitory or enhancing effect of the compound on the enzyme. |
| priorityDate | 2001-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.