abstract |
The invention relates to carboxylic acid amides of formula (I), in which R<1> to R<4>, Het, Z<1>, A, Ar, and m are defined as per claim 1, to their tautomers, their stereoisomers, their mixtures, their prodrugs and their salts, which exhibit valuable properties. The compounds of the aforementioned formula (I), in which R<4> represents a cyano group, represent valuable intermediate products for producing the remaining compounds of general formula (I), and the compounds of the aforementioned general formula (I), in which R<4> represents one of the amidino groups mentioned in claim 1, exhibit valuable pharmacological properties, in particular an anti-thrombotic action and a factor Xa inhibiting action. |