| abstract |
Remedies for nerve function failures such as central nerve damages including spinal damage and brain infarction having an excellent effect of promoting nerve regeneration which can be administered not only by injecting into a damaged site but also by various administration methods including intravenous administration, can be easily handled, can be stored over a long time and can be prepared in a large amount anytime. These remedies are prepared by using, as the active ingredient, one or more substances selected from among substance secreted from dendritic cells such as IL-12 and GM-CSF, substances inducing and proliferating dendritic cells, substances activating dendritic cells, substances inducing the expression of neurotrophic factors in nerve tissues, and substances inducing and proliferating microglias and macrophages in nerve tissues, vectors capable of expressing these substances, or dendritic cell subsets secreting neurotrophic factors such as NT-3, CNTF, TGF-β1, IL-6 and EGF. |