Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ce1bcbc8c01a47e9c1634ddc6564415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7596e7ce923c74580c60a001e4b8e51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a8861f8d84b959b12ec6652da154541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7856551a946c801c11d210aea4ab3dc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d600b011834b8f0a1978322336c61ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-415 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-56 |
filingDate |
2002-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_014b8689fef5f55e43719a333da9f2b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c592de983f9d2803a27cf7a2e08d0334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0181fce4720a5a25b88788b11a56e42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6949c993cb805ff57762268c7c77c0b9 |
publicationDate |
2002-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-02070716-A1 |
titleOfInvention |
Allergen ole e 9 from olea europaea, recombinant dna coding for said allergen, the production and use thereof |
abstract |
The invention relates to the production of the recombinant allergen Ole e 9 from Olea europaea in Pichia pastoris yeast for use in the diagnosis and treatment of allergies and to the system for isolating and purifying said allergen. The recombinant DNA coding for allergen Ole e 9 from olive pollen (Olea europaea) has been cloned and expressed. The above-mentioned allergen has β-1,3-glucanase activity and shows high homology with said proteins. Proteins homologous with said allergen have also been detected in other pollens from other members of the oleacea family (Syringa vulgaris, Ligustrum vulgare and Fraxinus excelsior). The recombinant protein produced in the yeast (Pichia pastoris) is isolated with high yields, it is correctly bonded and shows immunological properties equivalent to those of the natural allergen. Hence, said protein and homologous proteins, the modified forms derived therefrom, the derived fragments containing at least one allergenic epitope can be used in diagnosis and immunotherapy protocols. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4730764-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2315076-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006217896-A |
priorityDate |
2001-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |