Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1a230a17f5ab993cea98b1c689ee2af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b74fd535413d173136cad80e2bfb1ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e402c0bf971c40f2db9e4ed81174b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 |
filingDate |
2002-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bd0166add75fb999ca913eed07fbe46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_952acc0a89bfbc907a6dfd8f88a7d59b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80d6eb2b13b81870c59fe474faaa5d58 |
publicationDate |
2003-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-02068622-A3 |
titleOfInvention |
Crystal structure information of pnp synthase and the use thereof |
abstract |
The present invention relates to crystal structure information obtained from crystalline preparations of pyridoxine 5'-phosphate (PNP) synthase (PdxJ) and its use for the design of active site PNP synthase mutants and for the design and/or identification of inhibitors of PNP synthase. A further subject matter of the invention are PNP inhibitor molecules and their use in pharmaceutical compositions for the treatment and/or prevention of diseases caused by pathogens containing PNP synthase. |
priorityDate |
2001-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |