| abstract |
The invention relates to a novel complex for oral delivery of drugs, therapeutic protein / peptides and vaccines which are loaded in a Vitamin B12 (VB12) coupled particulate carrier system with spacers in between, the carrier system with spacers having a formula VB12 - R'/R'-N wherein, R' or R' is spacer and/or agents for derivatization of VB12 to provide either NH2 or COOH or SH groups, and N is the micro or nano particle carriers for the delivery of injectable drugs, therapeutic protein/peptides and vaccines. |