| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78941ed5a01bfbcd48376e1fdb485b19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65 |
| filingDate |
2002-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22dc3ccbcf422f142d0fadf64d1b1c60 |
| publicationDate |
2002-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02067870-A3 |
| titleOfInvention |
Composition and method for preventing and treating sinusoidal obstruction syndrome and radiation-induced liver disease |
| abstract |
The method for using matrix metalloproteinase ("MMP") inhibitors to prevent and treat Sinusoidal Obstruction Syndrome ("SOS"). In particular, the present invention provides a method of preventing and treating chemotherapy- and radiation-induced liver disease. This invention can be given prophylatically to patients who are receiving high dose chemotherapy and/or radiation and who are at risk for SOS or radiation-induced liver disease. This method may also be used to treat patients therapeutically who have developed SOS or radiation-induced liver disease. Because the development of chemotherapy or radiation-induced liver disease limits patient eligibility for several chemotherapeutic drugs, the present invention increases patient eligibility for many of these drugs. |
| priorityDate |
2001-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |