http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02066074-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74e2ebed8eb276ab7fc153aa06d90f16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c05cb12c81c891ad25b8cc39e0d1f523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5251690662243f63199428d7e396b134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f01f81b930d67957c9cba708f32649a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c481660f7e3a5ca29f9aacae5eae326f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K5-001 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2002-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69560e87f2ee5123256017a2375139e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d822a376351f5a7274c7c9eeeb963c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f2b29bb532bc41c19a628eac162879a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7e157edf6f5d7fddc61ecfe1df0f5c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98a0e7abfe338dfb840e619caf9cec10 |
| publicationDate | 2002-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-02066074-A2 |
| titleOfInvention | Method for assessing food allergenicity |
| abstract | A method for testing the allergenicity of a heterologous protein produced by a plant or animal that has been genetically modified to produce that protein is disclosed. The method includes the steps of: (a) sensitizing a newborn dog from an atopic dog colony with a first extract prepared from tissue of the genetically modified plant or animal and containing a mixture of plant or animal proteins and the heterologous protein, by injecting or feeding the extract into the newborn dog; (b) after a period sufficient to allow the dog to establish an immune response to the sensitizing extract, challenging the dog with the extract; (c) observing the degree of allergic response provoked; (d) if a detectable skin reaction is observed, comparing the degree of skin reaction observed with that observed by carrying out steps (a)-(c) above, but where the sensitizing step (a) or applying step (b) is carried out with a second plant or animal extract containing substantially the same proteins as the first extract but lacking the heterologous protein, and (e) if the degree of accordance with step (d), identifying the heterologous protein as a potential allergen in humans. Also disclosed is a dog for use in testing a biological substance for allergenicity in humans, and compositions useful in practicing the method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005113020-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2870456-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005113020-A2 |
| priorityDate | 2001-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.