http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0206522-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7aa61d485a8dfabd2a3f8dde13df9816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9f02625f688271c058b0c3d01b10132 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2001-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d15af24bb7d0d84cb1d991d3cf26ae0 |
publicationDate | 2002-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0206522-A2 |
titleOfInvention | Estrogen receptor gene polymorphisms as markers for determining a predisposition for low bone density |
abstract | The invention relates to a method of determining genetic predisposition to low or high bone mineral density of a patient, wherein low beone density is indicative of a predisposition to esteoporosis, esteopenia or bone fracture and high bone density is indicative of resistance to osteoporosis, osteopenia or bone fracture. The invention further relates to a marker at the estrogen receptor or equivalents thereof to prognose a response to esteoporosis therapy. As well, the invention relates to a method for determining osteoporosis susceptibility, prognosis and response to therapy based on a determination of the combination of the genotype at the estrogen receptor or at markers in linkage disequilibrium therewith, alone or together with other parameters such as age, or a therapeutic regimen. The invention further relates to screening assays to identify and select agents which can be used in the treatment of osteoporosis. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006084937-A1 |
priorityDate | 2000-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 349.