Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ac4503b38fa23551395af5ddf05e1eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7876e4f2d71b47b79fd883defff1e04c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_438bc04d4549bee39f074cc0633c68c2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da92ed2b7fa78d7791b4875391208425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c32070adec36aa362babe042fbd9346 |
publicationDate |
2002-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0206509-A2 |
titleOfInvention |
Glucose-1-phosphate thymidylyltransferase and method for selecting inhibitors thereof |
abstract |
There is provided a method of obtaining selecting agents which inhibit the enzyme glucose-1-phosphate thymidylyltransferase (Rm1A) based upon analysis of a model of the active and regulatory site (s) of Rm1A and interaction therewith by a potential inhibitory agent. The invention is based upon the provision of information on the structure of Rm1A obtained through X-ray diffraction studies since a crystallised form of Rm1A was obtained for the first time. The purified and crystallised from of Rm1A, obtained from Psemdomononas aeruginosa is also described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7778779-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109097496-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004044189-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004044189-A2 |
priorityDate |
2000-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |