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publicationDate 2002-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-02063028-A1
titleOfInvention Process for producing (3r,5s)-(e)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enic acid esters
abstract A process for producing a compound represented by the following general formula (IV): (IV) wherein R represents hydrogen, alkyl or aryl; characterized by reducing a compound selected from the group consisting of compounds represented by the following general formula (I): (I) wherein R is as defined above; compounds represented by the following general formula (II): (II) wherein R is as defined above; and compounds represented by the following general formula (III): (III) wherein R is as defined above; by treating optionally processed cells of a microorganism capable of stereoselectively reducing a keto group.
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