| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cf374ecaed27c8b9bd75d56acd7e801 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate |
2002-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b67bb7e4a978c04728f794a7e00670a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f7450d921fc3deab315462053ec78df |
| publicationDate |
2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02061114-A2 |
| titleOfInvention |
Water-soluble, fluorescent and mobile peptide substrates |
| abstract |
The present invention provides non-radioactively labeled synthetic substrates for enzymatic reactions which exhibit markedly improved solubility having the general structure *F-R1-L1-R2-PHc1-PS-PHc2-(R3-L-R4-T)y. These substrates may be designed to carry a charge to allow electrophoretic separation of substrates and reaction products. The invention also provides enzymatic activity assays for protein kinases, phosphatases and proteases utilizing the substrates of the invention, as well as methods of producing these substrates. In addition, the invention also provides libraries of the substrates, and methods of utilizing these libraries to select optimal synthetic peptide enzyme substrates for high-throughput screening assays. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006523203-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007141030-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007141030-A3 |
| priorityDate |
2001-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |