http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02059348-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64933c8ba4a402c32cddc2e4be869b05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61a5657ad885c694285bc62b102079d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9ded95450aac0dcc884179bf986359c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d841d11fd6a9a3cb221356c0d12f33f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-164 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2002-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd25187a68137338470304efa38db8cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6d2e6af7b8131f90fa15dd32ec13ab9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1ec7a700971775fa524ee05385179ea |
publicationDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-02059348-A2 |
titleOfInvention | Methods for determining the genetic affinity of microorganisms and viruses |
abstract | Selecting which sub-sequences in a database of nucleic acid such as 16S rRNA are highly characteristic of particular groupings of bacteria, microorganisms, fungi, etc. on a substantially phylogenectic tree. Also applicable to viruses comprising viral genomic RNA or DNA. A catalogue of highly characteristic sequences identified by this method is assembled to establish the genetic identity of an unknown organism. The characteristic sequences are used to design nucleic acid hybridization probes that include the characteristic sequence or its complement, or are derived from one or more characteristic sequences. A plurality of these characteristic sequences is used in hybridization to determine the phylogenetic tree position of the organism(s) in a sample. Those target organisms represented in the original sequence database and sufficient characteristic sequences can identify to the species or subspecies level. Oligonucleotide arrays of many probes are especially preferred. A hybridization signal can comprise fluorescence, chemiluminescence, or isotopic labeling, etc.; or sequences in a sample can be detected by direct means, e.g. mass spectrometry. The method's characteristic sequences can also be used to design specific PCR primers. The method uniquely identifies the phylogenetic affinity of an unknown organism without requiring prior knowledge of what is present in the sample. Even if the organism has not been previously encountered, the method still provides useful information about which phylogenetic tree bifurcation nodes encompass the organism. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004033720-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004033720-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2359289-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005142584-A1 |
priorityDate | 2001-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.