| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e559abcd8f120b071dc1162360867ffa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b0de178059b67f257ec0c37c8895153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_394ec43f88a0160aa85547aa9559f670
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0535b6cdb9b600bef18f53dd84b88f7a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate |
2002-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3453569b13ecfeea654973166f7afe7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a580e48892326eb10a4cbedcf1ed462b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f3d2250c99fc4fe3d0401a4f2289cf9 |
| publicationDate |
2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02059120-A1 |
| titleOfInvention |
Process for the preparation of isothiazole derivatives |
| abstract |
Method for preparing a compound (I): from the corresponding amine and an ether L-R3 (where L is a leaving group), by mixing the amine and the ether and then introducing a nitrogen-activating agent which activates the nitrogen atom adjacent the isothiazole ring to electrophilic attack. The activating agent is preferably added gradually over a period of several hours and is suitably a nitrogen silylating agent. The method can enhance reaction selectivity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009504721-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7973069-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007020460-A1 |
| priorityDate |
2001-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |