http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02058633-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-04 |
filingDate | 2002-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4107bdd2dc1e7af15011dd40d5403726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aa9531f291aad6e6ac5ed8313180fc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fd9e12d1d2918d2190b26ba25f7e9b |
publicationDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-02058633-A2 |
titleOfInvention | Solid- and solution -phase synthesis of heparin and other glycosaminoglycans |
abstract | Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of each of them. Additionally, the modular strategy provides the basis for the preparation of combinatorial libraries and parallel libraries of defined glycosaminoglycan oligosaccharides. The defined glycosaminoglycan structures may be used in high-throughput screening experiments to identify carbohydrate sequences that regulate a host of recognition and signal-transduction processes. The determination of specifi sequences involved in receptor binding holds great promise for the develpment of molecular tools which will allow modulation of processes underlying viral entry, angiog enesis, kidney diseases and diseases of the control nervous system. Notably, the present invention enables the automated synthesis of glycosaminoglycans in much the same fashion that peptides and oligonucleotides are currently assembled. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2272855-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104245718-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009098449-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2557086-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104245718-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011014793-A3 |
priorityDate | 2001-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 625.