http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02057789-A8

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filingDate 2002-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f68b85fc5a3abcac8f08b180dd3c76f4
publicationDate 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-02057789-A8
titleOfInvention Test for transmissible spongiform encephalopathies
abstract A method of detecting transmissible spongiform encephalopathies is described which involves (a) treating a sample of tissue, blood or a blood derivative from a test subject with alcohol and a detergent, (b) adding an agent which degrades normal prion protein (c) adding an agent which denatures abnormal prion protein, (d) adding a prion-specific antibody and (e) detecting binding of the antibody to the sample. Also described is a method of fixing abnormal prion protein to a substrate comprising (a) treating the protein or a sample suspected to contain the abnormal prion protein with alcohol and an anionic detergent and (b) adding a protease, in the presence of the substrate.
priorityDate 2001-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 22.