abstract |
Genes participating in the regulation of the activities of MMPs such as MT1-MMP and MT3-MMP are clarified and thus various biological activities and physiological phenomena in which MMPs participate are researched and developed. Because of having a characteristic sequence (for example, lacking the glycosaminoglycan attachment site) and being capable of inhibiting the activities of MT1-MMP, MT3-MMP, etc., N-Tes is useful in the research and development of useful drugs. |