Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d6c400bfc343eac6de8e47e37698312 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f16c6198061f05c1dae3bd9ddb1b064 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1288 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2001-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c7de71a1e3683e990ca3640f336a702 |
publicationDate |
2002-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-02051439-A2 |
titleOfInvention |
Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor |
abstract |
Methods and compositions are disclosed that are useful for the prevention and/or treatment of cardiovascular and cardiac diseases and disorders, or damage resulting from surgical or medical procedures that may cuase ischemic or ischemic/reperfusion damage in humans; and cardiovascular trauma. The beneficial effects of the compositions and methods are achieved through the use of pharmaceutical compositions that include agents that interfere with the production and/or biological activities of sphingolipids and their metabolites, particularly sphingosine (SPH) and sphingosine-1-phosphate (S-1-P). Also disclosed are methods for identifying and isolating therapeutic agents. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1933880-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9274129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9217749-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7794713-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2035362-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005325227-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9274130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1933880-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2035362-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1812797-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8741967-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10111841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7862812-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9133097-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1812797-A2 |
priorityDate |
2000-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |