| abstract |
Methods for increasing expression of the LDL receptor-related protein (LRP) in cells or animals are disclosed. The methods comprise treating the cells or animals with an HMG-CoA reductase inhibitor (statin). Such treatments are also useful for: reducing activity of LRP ligands in cells or animals, determining whether a particular condition is caused by insufficient or excess expression of an LRP, determining whether a particular protein is inactivitated by an LRP, and other similar applications. |