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publicationDate 2002-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0200016-A1
titleOfInvention Altered wool and hair fibres
abstract A method of altering the physical and/or chemical properties of hair or wool fibres. The method includes the steps of expressing one or more exogenous proteins in follicle cells of the hair or wool fibre, and/or over-expressing or under-expressing one or more endogenous proteins in follicle cells of the hair or wool fibre. The protein is expressed in at least one compartment of the hair follicle so that is interacts physically and/or chemically with native KAP and/or IF structural proteins and the interactions are relatively uniform in distribution throughout the compartment to thereby alter the properties of the hair or wool fibre without substantially affecting the structural integrity of the fibre. In one specific embodiment, silk proteins are expressed in the cortex of hair or wool fibres to thereby alter the properties of the hair or wool fibre.
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