Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c973b90bc7010d672522e6ef82e20ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb87544d79797a7a0f3b4110e7697557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c3ed663cfdb61e19ece07a8f95ae55f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cc3469cc898b6b74e83a2583fdd2fb1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
filingDate |
2001-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45e683eb6ddeb4af96d7ba999759619f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc8ef3748ddc9905b02bc674c4040cf5 |
publicationDate |
2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0197778-A2 |
titleOfInvention |
Amphotericin b structured emulsion |
abstract |
Parenteral compositions of oil-coated-Amphotericin B in structured-emulsion form, having LD50 of atleast 400mg/kg in mice and process for making the same have been described. The process essentially requires dispersing Amphotericin B in oily vehicle and dispersing emulsifier in the aqueous phase. The process of present invention is simple, cost effective and gives a stable product suitable for parenteral administration. Amphotericin B emulsion compositions prepared by the process of the present invention may be administered to human beings and animals for the treatment of fungal infections, with substantially equivalent or greater efficacy and low drug toxicity as compared to the conventional composition containing Amphotericin B and sodium desoxycholate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2398460-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2398460-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102395355-A |
priorityDate |
2000-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |