Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06dff2fa4a2404d4c4817f62296862a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61a7f6a9ed455a9d11716600339c2645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d5bdeb19332a6238ce9e12c3c167ecf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b57430246855a55769521a996c0f5c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d42a3470562101000f511c7de6f9ce78 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2001-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41add7da71610397f2ee87b3aa4a36d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_110a3f3aaa1c192f4604a5d49aaf2789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d4ea7773e8da3ac29901d2b69231445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec04e71631a0624bce6eff54e16182de |
publicationDate |
2001-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0192580-A2 |
titleOfInvention |
Lyophilizable and enhanced compacted nucleic acids |
abstract |
Counterions of polycations used to compact nucleic acids profoundly affect shape and stability of particles formed. Shape is associated with differential serum nuclease resistance and colloidal stability. A surrogate for determining such properties that is easy to measure is the turbidity parameter. Shape also affects the suitability and efficacy of compacted nucleic acid complexes for transfecting cells by various routes into a mammalian body. Moreover, counterions such as acetate can protect compacted nucleic acid complexes from adverse effects of lyophilization. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03091382-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9133459-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1359228-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03091382-A2 |
priorityDate |
2000-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |