| abstract |
Disclosed is a novel compound, represented by formula (1), in which oligonucleotide or analogue thereof that is capable of bonding with genes (DNA or RNA) site-specifically has pyrrolizine derivatives that form covalent bonding with specified base groups of the genes (DNA or RNA) and a process for preparing the same. Also, the present invention relates to a use of the compound in wide range, as site-specifically target substances in fields related of treatment diagnosis and analysis of gene-related diseases. Formula (1) wherein, R1, X, X', Y and n are as defined in the description. |