abstract |
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula (1) wherein one of X, Y, or Z is independently -S-, -O-, or > N-R4, the others are-CH¿2-;? (p) is an integer from 0 to 3 inclusive; m is an integer from 0 to 3 inclusive; n is an integer from 1 to 6 inclusive; R?3¿ is (C¿1-6?)-alkyl, (C1-6)-alkenyl, (C 1-6)-alkynyl or cycloalkyl; and R?1, R2 and R3¿ are hydrogen or specified substituents. These compounds are useful for treating diseases associated with smooth muscle disorders. |