| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7a7b7f887ae8ca70c82be1ffc68c3bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a12b18691834225968c82845b510ea83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e326d5c5e23c2d49515c47523b2e7cea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a9d40e8dce62386b0d3f938ab089add
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8e680f3cc4d522b58c8404d6c3555e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_995f3014aa16c4bcb7b3f5b8772e6551 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2001-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8357a3ab528135df973401e9e016f10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66f6c7f57dc844a902f308fba11607f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c8ba4a0245abf63f0696d92f19cd6cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e74142bfd49d173e405eeea9bd860a0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10f05d82b1f51502189c6a44aeb2eb96 |
| publicationDate |
2001-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0188175-A1 |
| titleOfInvention |
Process for the continuous production of dipeptide crystals in a membrane and hydro-cyclone reactor using a peptidase |
| abstract |
The invention relates to a process for the production of dipeptide crystals (generic formula AcXYNH2) with high purity (⊃ 95 %), by enzymatic synthesis with a protease in organic media of reversed micelles, starting from derivatives of the two constituent amino acids (AcXOEt and YNH2). A membrane and hydro-cyclone reactor was designed which enables the continuous and simultaneous synthesis and crystallisation of the dipeptides. The dipeptide crystals thus prepared are continuously removed and further separated from the remaining liquid by filtration or centrifugation. After drying, the crystals are dissolved in hot methanol. By decreasing the temperature, the dipeptide re-crystallises, originating a high purity product. After re-crystallisation the product is filtered and dried. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011145639-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5863647-B2 |
| priorityDate |
2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |