| abstract |
Disclosed is a process for selectively reducing a nitrile containing organic compound of formula (II) (in which R and R1 are independently lower alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; and n is 0-6) that also contains a sulphone moiety, the nitrile being reduced to a primary amine by use of borane or a substituted borane at a temperature of about -10 °C to 60 °C. |