http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0181912-A1

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filingDate 2000-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47776ac5026983f5d306306b4ec248b2
publicationDate 2001-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0181912-A1
titleOfInvention Metal cannula for extracting organic substances
abstract Solid phase microextraction (SPME) is the most significant microextraction technology for the chemical analysis of liquid and gaseous samples. The quantity of organic substances that can be extracted in this way is however limited. Long extraction times are required and the fragile fibre cannot be subjected to mechanical loads. The novel metal cannula allows dynamic extraction. The extraction yields are greater for shorter extraction times and at the same time, the mechanical stability of the extraction cannula is greater. The inner surface of the cannula is partially or completely covered by a polymer layer. The sample is repeatedly pushed or drawn through the cannula by suction at high speed. During this process, the organic substances of the sample matrix are enriched in the polymer layer. The volume of the polymer layer determines the maximum quantity extractable and is significantly greater than in SPME. The geometry of the cannula ensures short diffusion paths and therefore short extraction times. The metal cannula can be provided with a plastic head and placed on the glass body of a syringe. The syringe body is also provided with an inlet for rinsing gas so that the extracted substances can be rinsed out of the cannula in the direction of the cannula tip during thermal desorption.
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Total number of triples: 25.