Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_229a467e91b99756604d9c7ea3b94bda http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba1a921b4868fde3bb08aa2f7c181e4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_291fa187e998635ac3b93c9a77a1f28d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ff67d26deeca1d359fc239f5e21f0a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebf0b76fff057891f6729cf3137f94d0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 |
filingDate |
2001-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c829672e07c50de4c43b395c1f92a710 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70bfbfeb024dc493c4c42af919019b2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_111929227b10f96b1b1d3cf7166ec5c8 |
publicationDate |
2002-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0179842-A3 |
titleOfInvention |
Method for identifying regulators of protein-age formation |
abstract |
The invention relates to methods for identifying compounds which affect cellular stress. In particular, the method relates to identifying compounds which inhibit protein advanced glycation end product formation, where the compounds are carbonyl scavengers which inhibit the formation. The assay involves combing the substance of interest with histone H1 and ADP-ribose, and then measuring fluorescence and protein cross linking. Various inhibitors of protein AGE glycation have been identified, using this assay. |
priorityDate |
2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |